Tub114
Tub114 is a drug-linker conjugate for ADC. Tub114 is a Tubulysin B (HY-N1243) analog with a stable hydrophilic linker. Tub114 can be used for synthesis of ADCs[1].
Product Specifications
CAS Number
[2361406-35-9]
UNSPSC
12352211
Target
Drug-Linker Conjugates for ADC; Microtubule/Tubulin
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(C=CC1=O)N1CCCC(N[C@@H](CCCCNC(COCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)C(NCCCC(NC(C=C2C[C@H](NC(C3=CSC([C@@H](C[C@@H](N(C([C@@H](NC(C(C)(N(C)C)C)=O)[C@H](CC)C)=O)C)C(C)C)OC(C)=O)=N3)=O)C[C@@H](C(O)=O)C)=C(C=C2)O)=O)=O)=O
Molecular Formula
C76H124N10O24S
Molecular Weight
1593.92
References & Citations
[1]Guo H, et al. The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy. Front Pharmacol. 2025 Feb 10;16:1532104.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Curated Selection
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