Tub114
Tub114 is a drug-linker conjugate for ADC. Tub114 is a Tubulysin B analog with a stable hydrophilic linker. Tub114 can be used for synthesis of ADCs[1].
Product Specifications
CAS Number
2361406-35-9
UNSPSC
12352211
Target
Drug-Linker Conjugates for ADC; Microtubule/Tubulin
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(C=CC1=O)N1CCCC(N[C@@H](CCCCNC(COCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)C(NCCCC(NC(C=C2C[C@H](NC(C3=CSC([C@@H](C[C@@H](N(C([C@@H](NC(C(C)(N(C)C)C)=O)[C@H](CC)C)=O)C)C(C)C)OC(C)=O)=N3)=O)C[C@@H](C(O)=O)C)=C(C=C2)O)=O)=O)=O
Molecular Formula
C76H124N10O24S
Molecular Weight
1593.92
References & Citations
[1]Guo H, et al. The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy. Front Pharmacol. 2025 Feb 10;16:1532104.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470029-100 1x 100 µL
Fibronectin (TV-1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680181-100 1x 100 µL
CD59 (heavy chain of Protectin) (BRA-10G), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC741227-100 1x 100 µL
Thyroglobulin (TGB04 + TGB05), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680183-500 1x 500 µL
Cytochrome C (Mitochondrial Marker) (7H8.2C12), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details