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EGFR ligand-14

EGFR ligand-14 is an EGFR ligand. EGFR ligand-14 can be used for the synthesis of SJF-1521.

Product Specifications

CAS Number

1792968-00-3

UNSPSC

12352005

Target

EGFR; Ligands for Target Protein for PROTAC

Related Pathways

JAK/STAT Signaling; PROTAC; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

FC1=CC(COC2=CC=C(NC3=C4C=C(C5=CC=CC=C5)C=CC4=NC=N3)C=C2Cl)=CC=C1

Molecular Formula

C27H19ClFN3O

Molecular Weight

455.91

References & Citations

[1]Burslem GM, et al. The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study. Cell Chem Biol. 2018 Jan 18;25 (1) :67-77.e3.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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