EGFR ligand-14
EGFR ligand-14 is an EGFR ligand. EGFR ligand-14 can be used for the synthesis of SJF-1521 (HY-131865) .
Product Specifications
CAS Number
[1792968-00-3]
UNSPSC
12352005
Target
EGFR; Ligands for Target Protein for PROTAC
Related Pathways
JAK/STAT Signaling; PROTAC; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
FC1=CC(COC2=CC=C(NC3=C4C=C(C5=CC=CC=C5)C=CC4=NC=N3)C=C2Cl)=CC=C1
Molecular Formula
C27H19ClFN3O
Molecular Weight
455.91
References & Citations
[1]Burslem GM, et al. The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study. Cell Chem Biol. 2018 Jan 18;25 (1) :67-77.e3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
