RSK2-IN-6

RSK2-IN-5 (compoud C2) is a p90 ribosomal S6 kinase 2 (RSK2) inhibitor with a Kd of 856 nM. RSK2-IN-5 exhibits antitumor activity against breast cancer and melanoma cancer cells[1].

Product Specifications

CAS Number

[304474-86-0]

UNSPSC

12352005

Target

Ribosomal S6 Kinase (RSK)

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

O=C(C1=CC=CC([N+]([O-])=O)=C1)NNC2=C3C(CCCC4)=C4SC3=NC=N2

Molecular Formula

C17H15N5O3S

Molecular Weight

369.40

References & Citations

[1]Yue Zhao, et al. Discovery of novel p90 ribosomal S6 kinase 2 inhibitors for potential cancer treatment through ligand-based and structure-based virtual screening methods. Chemometrics and Intelligent Laboratory Systems. Volume 217, 15 October 2021, 104402