IAJD-97
IAJD-97 is a single-component ionizable amphiphilic Janus dendrimer carrier targeting mRNA delivery, which self-assembles into dendrimersomes (DNPs) via pH-responsive mechanisms to efficiently encapsulate and protect mRNA, while facilitating cellular uptake and endosomal escape through ionizable amine groups. IAJD-97 is promising for research of cancers[1].
Product Specifications
CAS Number
[2857089-36-0]
UNSPSC
12352005
Target
Biochemical Assay Reagents
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(CCCN1CCN(CC1)CCO)OCC2=CC(OCC(CCCC)CC)=C(C(OCC(CCCC)CC)=C2)OCC(CCCC)CC
Molecular Formula
C41H74N2O6
Molecular Weight
691.04
References & Citations
[1]Arshad M, et al. Accelerated Ten-Gram-Scale Synthesis of One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer 97. Biomacromolecules. 2024 Oct 14;25 (10) :6871-6882.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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