U-80125
U80215, a dansylated peptide, is a competitive human renin inhibitor with the IC50 of 2.3 μM. U80215 shows excitation and emission maxima at 340 and 530 nm[1].
Product Specifications
CAS Number
123300-09-4
UNSPSC
12352100
Target
Renin
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
O=C([C@H]([C@H](CC)C)NC([C@H](C(C)C)CC([C@H](CC(C)C)NC([C@H](CC1=CN=CN1)NS(=O)(C2=CC=CC3=C(N(C)C)C=CC=C32)=O)=O)O)=O)NCC4=NC=CC=C4
Molecular Formula
C42H60N8O6S
Molecular Weight
805.04
References & Citations
[1]Epps DE, et al. An experimental method for the determination of enzyme-competitive inhibitor dissociation constants from displacement curves: application to human renin using fluorescence energy transfer to a synthetic dansylated inhibitor peptide. Anal Biochem. 1989 Aug 15;181 (1) :172-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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