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Mal-Val-Lys-PAB-MMAE (TFA)

Mal-Val-Lys-PAB-MMAE TFA is a drug-linker conjugate for ADC. Mal-Val-Lys-PAB-MMAE TFA consists of a Tubulin inhibitor (MMAE) (HY-15162) and a linker (Mal-Val-Lys-PAB) . Mal-Val-Lys-PAB-MMAE TFA can be used for synthesis of ADCs[1].

Product Specifications

UNSPSC

12352005

Target

Drug-Linker Conjugates for ADC; Microtubule/Tubulin

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton

Field of Research

Cancer

Purity

97.91

Smiles

O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCCN)NC([C@H](C(C)C)NC(CCCCCN4C(C=CC4=O)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O.O=C(O)C(F)(F)F

Molecular Formula

C70H107F3N10O16

Molecular Weight

1401.65

References & Citations

[1]Chen T Z, et al. Novel hydrophilic glycosylation linker, synthesis and application thereof. CN115429889A. 2022-12-06.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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