Mal-Val-Lys-PAB-MMAE
Mal-Val-Lys-PAB-MMAE is a drug-linker conjugate for ADC. Mal-Val-Lys-PAB-MMAE consists of a Tubulin inhibitor (MMAE) (HY-15162) and a linker (Mal-Val-Lys-PAB) . Mal-Val-Lys-PAB-MMAE can be used for synthesis of ADCs[1].
Product Specifications
CAS Number
[2435608-81-2]
UNSPSC
12352100
Target
Drug-Linker Conjugates for ADC; Microtubule/Tubulin
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCCN)NC([C@H](C(C)C)NC(CCCCCN4C(C=CC4=O)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
Molecular Formula
C68H106N10O14
Molecular Weight
1287.63
References & Citations
[1]Chen T Z, et al. Novel hydrophilic glycosylation linker, synthesis and application thereof. CN115429889A. 2022-12-06.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Curated Selection
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