Anti-inflammatory agent 105
Anti-inflammatory agent 105 (Compound 12) is an anti-inflammatory compound. The IC50 of Anti-inflammatory agent 105 for the inhibition of TNF-α synthesis and release in the human macrophage cell line U937 is 0.124 nM[1].
Product Specifications
CAS Number
382630-14-0
UNSPSC
12352100
Target
TNF Receptor
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=CC=CO1)O[C@]2([C@@]3([C@@]([C@@]4([H])[C@]([C@H](C3)O)([C@@]5(C([C@H](C4)F)=CC(C=C5)=O)C)Cl)([H])C[C@H]2C)C)C(OC)=O
Molecular Formula
C27H30ClFO7
Molecular Weight
520.97
References & Citations
[1]Sandham DA, et al. Synthesis and biological properties of novel glucocorticoid androstene C-17 furoate esters. Bioorg Med Chem. 2004 Oct 1;12 (19) :5213-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470812-500 1x 500 µL
Tyrosinase (OCA1/812), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC941927-100 1x 100 µL
SOX9 / SRY-box 9 (PCRP-SOX9-1A2), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740688-500 1x 500 µL
Cytokeratin 8 (C-43), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC472205-100 1x 100 µL
PGP9.5 / UchL1 (pan-Neuronal Marker) (rUCHL1/775), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details