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Anti-inflammatory agent 104

Anti-inflammatory agent 104 (Compound 26) is an anti-inflammatory compound. The IC50 of Anti-inflammatory agent 104 for the inhibition of TNF-α synthesis and release in the human macrophage cell line U937 is 0.024 nM. Anti-inflammatory agent 104 can reduce eosinophils in rat lungs by 63%[1].

Product Specifications

CAS Number

[382630-23-1]

UNSPSC

12352100

Target

TNF Receptor

Related Pathways

Apoptosis

Field of Research

Inflammation/Immunology

Smiles

O=C(C1=C(C=CS1)C)O[C@]2([C@@]3([C@@]([C@@]4([H])[C@]([C@H](C3)O)([C@@]5(C([C@H](C4)F)=CC(C=C5)=O)C)Cl)([H])C[C@H]2C)C)C(OC)=O

Molecular Formula

C28H32ClFO6S

Molecular Weight

551.07

References & Citations

[1]https://patents.google.com/patent/WO2002000679A2/en?oq=WO2002000679+A2

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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