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MGluR2 modulator 6

MGluR2 modulator 6 (Compound 25-a) is a mGluR2 modulator. mGluR2 modulator 6 has anticonvulsant activity in the 6Hz epilepsy model, and the effect is better when combined with Levetiracetam (HY-B0106) . mGluR2 modulator 6 can be used in the research of epilepsy[1].

Product Specifications

CAS Number

[1127498-73-0]

UNSPSC

12352005

Target

MGluR

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C1C(Cl)=C(N2CCC(CC2)C3=CC=C(C=C3F)F)C=CN1CCCC

Molecular Formula

C20H23ClF2N2O

Molecular Weight

380.86

References & Citations

[1]Brian D KLEIN, et al. Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use. WO2015110435A1. 2015-07-30.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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