HCV NS5B polymerase-IN-3
HCV NS5B polymerase-IN-3 (Compound 30a) is an inhibitor of the HCV NS5B polymerase. HCV NS5B polymerase-IN-3 exhibits anti-HCV activity in the Huh7 replicon cell line with an EC50 of 0.23 μM and shows no obvious cytotoxicity. HCV NS5B polymerase-IN-3 can be used in research related to the hepatitis C virus[1].
Product Specifications
CAS Number
1255860-45-7
UNSPSC
12352005
Target
HCV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O[C@H]1[C@]2(CCO2)[C@H](N(C=CC3=O)C(N3)=O)O[C@@H]1CO[P](OC4=CC=CC=C4)(N[C@@H](C)C(OCC(C)C)=O)=O
Molecular Formula
C24H32N3O10P
Molecular Weight
553.50
References & Citations
[1]Jonckers TH, et al. Nucleotide prodrugs of 2'-deoxy-2'-spirooxetane ribonucleosides as novel inhibitors of the HCV NS5B polymerase. J Med Chem. 2014 Mar 13;57 (5) :1836-44.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC041268-500 1x 500 µL
Creatine Kinase-BB (CK-BB) (CKBB/1268), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040520-100 1x 100 µL
Mucin 1 / EMA / Episialin / CD227 (MUC1/520), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
![Myotilin (MYOT) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5E11]](https://cdn.genprice.uk/products/937/68dd1b82061270361ea1ef2b/imageurl/ta809575am.webp)
TA809575AM 100 µL
Myotilin (MYOT) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5E11]
Sign In for Pricing
View Details 
