GPR40 agonist 8
GPR40 agonist 8 (Compound 2) is a GPR40 agonist with an EC50 of 5 nM for hGPR40 Ca2+. GPR40 agonist 8 can be used in the research of diseases such as Type II diabetes and obesity[1].
Product Specifications
CAS Number
[1905451-62-8]
UNSPSC
12352211
Target
Calcium Channel; Free Fatty Acid Receptor
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Metabolic Disease
Smiles
CC1=C(C2=CSC3=CC=C(COC4=CC=C([C@H](CC(O)=O)C#CC)C=C4)C=C32)C=CC=C1
Molecular Formula
C28H24O3S
Molecular Weight
440.55
References & Citations
[1]Gee-Hong Kuo, et al. Substituted benzothiophenyl derivatives as gpr40 agonists for the treatment of type ii diabetes. WO2016057731A1. 2016-04-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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