C-Kit-IN-11
C-Kit-IN-11 (Compound A7) is a c-Kit inhibitor with an IC50 of 76 nM for Mo7e cells. c-Kit-IN-11 can be used for inflammatory like asthma and malignant cancers research[1].
Product Specifications
CAS Number
[1185279-55-3]
UNSPSC
12352005
Target
C-Kit
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C1C(C2=CC(NC3=NOC(C4=CC=CC=C4)=N3)=CC=C2C)=CC5=C(N1C)C=C(C)N=C5
Molecular Formula
C25H21N5O2
Molecular Weight
423.47
References & Citations
[1]Li X L, et al. Heterocyclic compounds and compositions as c-kit and pdgfr kinase inhibitors. WO2009105712A1. 2009-08-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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