Salvianolic acid A derivative-1
Salvianolic acid A derivative-1 (Compound SAA-30) is a orally active derivative of Salvianolic acid A (HY-N0318) . Salvianolic acid A derivative-1 binds to transgelin with a KD of 2.39 μM. Salvianolic acid A derivative-1 promotes cell contractions by facilitating the aggregation of actin. Salvianolic acid A derivative-1 can be used for prevention of myocardial ischemia or other diseases associated with IR tissue injuries[1].
Product Specifications
UNSPSC
12352005
Target
Arp2/3 Complex
Related Pathways
Cytoskeleton
Field of Research
Cardiovascular Disease
Smiles
OC1=CC=C(/C=C/C(O[C@@H](C(OCC)=O)CC2=CC(O)=CC=C2)=O)C(/C=C/C3=CC(O)=C(O)C=C3)=C1O
Molecular Formula
C28H26O9
Molecular Weight
506.50
References & Citations
[1]Zhong W, et al. Salvianolic acid A targeting the transgelin-actin complex to enhance vasoconstriction. EBioMedicine. 2018 Nov;37:246-258.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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