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G256 (dihydrochloride)

G256 (Compound 1) (dihydrochloride) is an amidinohydrazone. G256 (dihydrochloride) can also be considered as a Schiff’s base of aminoguanidine. G256 (dihydrochloride) exhibits antiarrhythmic activity. G256 (dihydrochloride) is the reduced form of NOH-G256 by microsomal enzyme preparation from rabbit and rat liver homogenates in the presence of NADPH and NADH[1].

Product Specifications

CAS Number

[134867-96-2]

UNSPSC

12352101

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Cardiovascular Disease

Smiles

N=C(N)N/N=C(C1=CC=CC=C1)\C2=C(N)C=CC(Cl)=C2.Cl.Cl

Molecular Formula

C14H16Cl3N5

Molecular Weight

360.67

References & Citations

[1]Clement, B., et al., (1994) . Cytochrome P450-dependent N-hydroxylation of an aminoguanidine (amidinohydrazone) and microsomal retroreduction of the N-hydroxylated product. Xenobiotica; the fate of foreign compounds in biological systems, 24 (7), 671–688.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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