CDD-1349
CDD-1349 (Compound 15) is a BRDT-BD2/BRD4-BD2 selective inhibitor. CDD-1349is an analog with sixfold selectivity for BRDT-BD2 versus BRD4-BD2. CDD-1349 has an IC50 of 22 nM against BRDT. CDD-1349 can be studied in research on nonhormonal contraceptive agent[1].
Product Specifications
CAS Number
[2757619-90-0]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Related Pathways
Epigenetics
Field of Research
Endocrinology
Smiles
O=C(C1=CC=C(C(NC)=O)C=C1)NC2=CC(NC(C3=CC(C(C4=C(C)C=C(N)N=C4)=NN5C)=C5C=C3)=O)=CC=C2C
Molecular Formula
C31H29N7O3
Molecular Weight
547.61
References & Citations
[1]Yu, Z., et al., (2021) . Discovery and characterization of bromodomain 2-specific inhibitors of BRDT. Proceedings of the National Academy of Sciences of the United States of America, 118 (9), e2021102118.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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