Tubulin-IN-52
Tubulin-IN-52 is a tubulin inhibitor. Tubulin-IN-52 demonstrates significant cytotoxicity toward a variety of cancer cell types including prostate, lung, and ovarian cancers with strong activity toward highly aggressive cancer lines (IC50 = 0.9-3.8 mM) . Tubulin-IN-52 significantly inhibits the growth of established tumors without noticeable toxicity. Tubulin-IN-52 can be used for the study of cancer[1].
Product Specifications
CAS Number
[2099064-75-0]
UNSPSC
12352005
Target
Microtubule/Tubulin
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(NC1=NC2=C(N1)C=C(C(C3=CC=C(N(C4COC4)C)C=C3)=O)C=C2)OC
Molecular Formula
C20H20N4O4
Molecular Weight
380.40
References & Citations
[1]Cheong JE, et al. Synthesis and anticancer activity of novel water soluble benzimidazole carbamates. Eur J Med Chem. 2018 Jan 20;144:372-385.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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