ACLY-IN-2
ACLY-IN-2 (Compound 7) has inhibitory effect against human ATP citrate lyase (hACLY), with an IC50 of less than 1 nM. ACLY-IN-2 can be studied in research on liver-related diseases, type-2 diabetes, autoimmunity, and cancer[1].
Product Specifications
CAS Number
3009136-86-8
UNSPSC
12352101
Target
ATP Citrate Lyase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Smiles
O=C(C1=CC2=C(O)C(Cl)=C1)OCCOC3=CC=CC=C3C4=CC(NS2(=O)=O)=C(F)C=C4F
Molecular Formula
C21H14ClF2NO6S
Molecular Weight
481.85
References & Citations
[1]Stephen Lawrence Pinkosky, et al., Macrocyclic inhibitors of atp citrate lyase. WO2023215220A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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