Refinicopan
Refinicopan is a complement factor D inhibitor with an IC50 of 10 nM. Refinicopan inhibits rabbit erythrocyte hemolysis with an IC50 of 41 nM. Refinicopan exhibits excellent pharmacokinetic and pharmacodynamic activity[1].
Product Specifications
CAS Number
2922808-66-8
UNSPSC
12352005
Target
Complement System
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
NCC1=CC=CC(C2=CC(N3CCC4(CC3)CC4)=CC(COC5=C(C=CC=C5)CC(O)=O)=C2)=C1
Molecular Formula
C29H32N2O3
Molecular Weight
456.58
References & Citations
[1]Jun Lou, et al. Compound as complement factor D inhibitor, and pharmaceutical composition and application thereof. CN. CN115894367 A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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