Refinicopan

Refinicopan is a complement factor D inhibitor with an IC50 of 10 nM. Refinicopan inhibits rabbit erythrocyte hemolysis with an IC50 of 41 nM. Refinicopan exhibits excellent pharmacokinetic and pharmacodynamic activity[1].

Product Specifications

CAS Number

[2922808-66-8]

UNSPSC

12352005

Target

Complement System

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

NCC1=CC=CC(C2=CC(N3CCC4(CC3)CC4)=CC(COC5=C(C=CC=C5)CC(O)=O)=C2)=C1

Molecular Formula

C29H32N2O3

Molecular Weight

456.58

References & Citations

[1]Jun Lou, et al. Compound as complement factor D inhibitor, and pharmaceutical composition and application thereof. CN. CN115894367 A.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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