Lotixparib
Lotixparib (Example 1) is an inhibitor of poly (ADP-ribose) polymerase-1 (PARP-1) . Lotixparib has cytoprotective effect against a retinal disease. Lotixparib can be studied in research for PARP-1-associated diseases[1].
Product Specifications
CAS Number
2640677-63-8
UNSPSC
12352005
Target
PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Others
Smiles
N#CC1=CC=C(N2CCN(CCCC3=CC4=C(C(N3)=O)C(F)=CC=C4)CC2)C=C1
Molecular Formula
C23H23FN4O
Molecular Weight
390.45
References & Citations
[1]Eunhee Kim, et al., Isoquinolinone derivative, preparation method therefor, and pharmaceutical composition, comprising same as active ingredient, for prevention or treatment of poly (adp-ribose) polymerase-1 (parp-1) -associated disease. WO2021086077A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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