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Lorotomidate

Lorotomidate (Example 16) is a GABAA receptor agonist. Lorotomidate has anaesthetic effects (ED50: i.v., 2 mg/kg in KM mice; LD50: 46.5 mg/kg in KM mice) . Lorotomidate has no inhibitory effect on the secretion of corticosteroids in animals, and thus has good safety[1].

Product Specifications

CAS Number

2093287-60-4

UNSPSC

12352005

Target

GABA Receptor

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

C[C@H](C1=CC=CC=C1)N2C(C(OCC)=O)=C(N=C2)F

Molecular Formula

C14H15FN2O2

Molecular Weight

262.28

References & Citations

[1]Qinggeng, Li, et al. Etomidate derivative and intermediate, preparation method and use thereof. Patent. WO2017059827A1

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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