Lorotomidate
Lorotomidate (Example 16) is a GABAA receptor agonist. Lorotomidate has anaesthetic effects (ED50: i.v., 2 mg/kg in KM mice; LD50: 46.5 mg/kg in KM mice) . Lorotomidate has no inhibitory effect on the secretion of corticosteroids in animals, and thus has good safety[1].
Product Specifications
CAS Number
2093287-60-4
UNSPSC
12352005
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
C[C@H](C1=CC=CC=C1)N2C(C(OCC)=O)=C(N=C2)F
Molecular Formula
C14H15FN2O2
Molecular Weight
262.28
References & Citations
[1]Qinggeng, Li, et al. Etomidate derivative and intermediate, preparation method and use thereof. Patent. WO2017059827A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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