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Envometinib

Envometinib (Compound B) is a dual-MEK inhibitor that works through Deep Cyclic Inhibition (DCI) . Envometinib has antitumor activity in various in vivo models. Envometinib can be studied in RAS and RAF mutated cancer such as colorectal cancer and melanoma[1].

Product Specifications

CAS Number

[2952542-22-0]

UNSPSC

12352005

Target

MEK

Related Pathways

MAPK/ERK Pathway

Field of Research

Cancer

Smiles

CN(CC(C1=C(OC2=O)C=C(OC(N(C)C)=O)C=C1)=C2CC3=C(C(NS(NC)(=O)=O)=CC=C3)Cl)C

Molecular Formula

C23H27ClN4O6S

Molecular Weight

523.00

References & Citations

[1]Brett Matthew HALL, et al., MEK immune oncology inhibitors and therapeutic uses thereof for treating cancer. WO2025010287A2.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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