Angexostat
Angexostat (Compound 2) is an inhibitor of xanthine oxidase. Angexostat exhibits high permeability. Angexostat inhibits CYP2C9 with an IC50 of 18.1 μM. Angexostat can be studied in research for xanthine oxidase-related diseases such as hyperuricemia and gout[1].
Product Specifications
CAS Number
[2640653-91-2]
UNSPSC
12352005
Target
Xanthine Oxidase
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
N#CC1=C(CCC(F)(C2)F)C2=C(C3=CC(O)=C(C(O)=O)C=C3)S1
Molecular Formula
C16H11F2NO3S
Molecular Weight
335.33
References & Citations
[1]Yang Zhang, et al., Thiophene derivatives as xanthine oxidase inhibitors and application thereof . WO2021083319.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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