NPRA agonist-11
NPRA agonist-11 (Example 161) is an NPRA (NPR1) agonist, with AC50 values of 1.681 μM and 0.989 μM for humans and monkeys, respectively. NPRA agonist-11 can be used in the research of cardiovascular diseases and other disorders[1].
Product Specifications
CAS Number
[3055143-61-5]
UNSPSC
12352005
Target
Natriuretic Peptide Receptor (NPR)
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
CN(C1=NC(N[C@H](C(C=N2)=CN2C)CN(CCC3)C[C@H]3C)=C(C[C@H](C4=CC(F)=CC=C4)CC5)C5=N1)[C@@H]([C@](CC6)([H])CC[C@H]6C(O)=O)CC
Molecular Formula
C37H52FN7O2
Molecular Weight
645.85
References & Citations
[1]Daniela Angst, et al. Hydroquinazoline derivatives for the treatment of a disease or disorder. WO2024180499A1. 2024-09-06.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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