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KAT6A/KAT7-IN-4

KAT6A/KAT7-IN-4 (Example 230) is a KAT6A and KAT7 inhibitor. KAT6A/KAT7-IN-4 has IC50 values of both ≤ 1 nM for KAT6A and KAT7. KAT6A/KAT7-IN-4 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-4 also inhibits tumor cell proliferation, with an IC50 of ≤ 100 nM for CAMA-1. KAT6A/KAT7-IN-4 can be used in the study of cancer[1].

Product Specifications

CAS Number

[3092067-21-2]

UNSPSC

12352005

Target

Histone Acetyltransferase

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=S(C1=C(OC)C=C(C(N2C[C@@H](C)O[C@H](C)C2)=O)C=C1OC)(NC3=NOC4=C3CC5(C6=C4C=C(N7CCC7)C=C6)CC5)=O

Molecular Formula

C31H36N4O7S

Molecular Weight

608.71

References & Citations

[1]Brian Thomas Jones, et al. Chemical compounds and uses thereof. WO2025136811A1. 2025-06-26.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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