KAT6A/KAT7-IN-2
KAT6A/KAT7-IN-2 (Example 177) is a KAT6A and KAT7 inhibitor. KAT6A/KAT7-IN-2 has IC50 values of both ≤ 1 nM for KAT6A and KAT7. KAT6A/KAT7-IN-2 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-2 also inhibits tumor cell proliferation, with an IC50 of ≤ 100 nM for CAMA-1. KAT6A/KAT7-IN-2 can be used in the study of cancer[1].
Product Specifications
CAS Number
[3092066-69-5]
UNSPSC
12352005
Target
Histone Acetyltransferase
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(NC)C1=CC(OC)=C(S(=O)(NC2=NOC3=C2CC4(C5=C3C=C(N6CCC6)C=C5)CC4)=O)C(OC)=C1
Molecular Formula
C26H28N4O6S
Molecular Weight
524.59
References & Citations
[1]Brian Thomas Jones, et al. Chemical compounds and uses thereof. WO2025136811A1. 2025-06-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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