RNase L ligand 3
RNase L ligand 3 is a RNase L ligand. RNase L ligand 3 can be used for synthesis of F3-PEG8-RiboTAC (HY-176259) [1].
Product Specifications
CAS Number
[3036649-51-8]
UNSPSC
12352100
Target
DNA/RNA Synthesis; PROTACs
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Field of Research
Cancer
Smiles
NC1=C(C2=CC(C3=CC=C(CN(C)[C@@H](C4=CC=CC=C4)C(NC)=O)C=C3)=CC=C2)SC=C1
Molecular Formula
C27H27N3OS
Molecular Weight
441.59
References & Citations
[1]Meyer SM, et al. Linker Optimization Enhances the Potency of Ribonuclease-Targeting Chimeras in Cancer Models. J Med Chem. 2025 Jun 26;68 (12) :12881-12903.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RNASE L
Curated Selection
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