LRRK2-IN-19
LRRK2-IN-19 is a PROTAC target protein ligand that can be used to synthesize PROTAC JH-XII-03-02 (HY-155150) . JH-XII-03-02 is a highly potent and selective LRRK2 PROTAC degrader, which can be used in Parkinson's disease research[1].
Product Specifications
CAS Number
[2839667-09-1]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; LRRK2
Related Pathways
Autophagy; PROTAC
Field of Research
Neurological Disease
Smiles
CC1(CC1)OC2=CC3=C(C=C2)NN=C3C4=CC(N5CCNCC5)=NC=N4
Molecular Formula
C19H22N6O
Molecular Weight
350.42
References & Citations
[1]Hatcher JM, et al. Development of a highly potent and selective degrader of LRRK2. Bioorg Med Chem Lett. 2023 Oct 1;94:129449.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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