(S, S, S) -Me-AHPC-amide-C3-alkyne
(S, S, S) -Me-AHPC-amide-C3-alkyne is an E3 ligase ligand-linker conjugate, used for the synthesis of (S) -JWZ-5-13 (HY-161828A) [1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
C#CCCCC(N[C@@H](C(C)(C)C)C(N1C[C@@H](O)C[C@H]1C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O
Molecular Formula
C29H38N4O4S
Molecular Weight
538.70
References & Citations
[1]Ji W, et al. Discovery of bivalent small molecule degraders of cyclin-dependent kinase 7 (CDK7) . Eur J Med Chem. 2024 Oct 5;276:116613.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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