DRP1 Allosteric-IN-3
DRP1 Allosteric-IN-3 (Compound 2b) is an allosteric inhibitor of DRP1. Its IC50 value for the DRP1:MiD49 protein-protein interaction is 11 μM. DRP1 Allosteric-IN-3 can be used to study various diseases related to mitochondrial division disorders[1].
Product Specifications
CAS Number
[3056559-92-0]
UNSPSC
12352005
Target
Dynamin
Related Pathways
Cytoskeleton
Field of Research
Cancer; Metabolic Disease; Neurological Disease; Cardiovascular Disease
Smiles
O=C(C(C)C)NC1=CC2=C(N=C(C3=CC=CC=C3)C=C2N(C)C)C=C1
Molecular Formula
C21H23N3O
Molecular Weight
333.43
References & Citations
[1]Staben LR, et al. Systematic Variation of Pyrrolobenzodiazepine (PBD) -Dimer Payload Physicochemical Properties Impacts Efficacy and Tolerability of the Corresponding Antibody-Drug Conjugates. J Med Chem. 2020 Sep 10;63 (17) :9603-9622.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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