DRP1 Allosteric-IN-1
DRP1 Allosteric-IN-1 (Compound 1) is an allosteric inhibitor of DRP1 with an IC50 value for the DRP1:MiD49 protein-protein interaction of 3.6 μM. DRP1 Allosteric-IN-1 can be used to study various diseases related to mitochondrial division disorders[1].
Product Specifications
CAS Number
[1359386-11-0]
UNSPSC
12352005
Target
Dynamin
Related Pathways
Cytoskeleton
Field of Research
Cancer; Metabolic Disease; Neurological Disease; Cardiovascular Disease
Smiles
O=C(C(C)C)NC1=CC2=C(N=C(C3=CC=CC=C3)C=C2OCC)C=C1
Molecular Formula
C21H22N2O2
Molecular Weight
334.41
References & Citations
[1]Furuya T, et al. Discovery of Potent Allosteric DRP1 Inhibitors by Disrupting Protein-Protein Interaction with MiD49. ACS Med Chem Lett. 2023 Jul 24;14 (8) :1095-1099.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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