Di (MMY-SJG) -Ph-prop-2-yne-1-sulfonic acid
Di (MMY-SJG) -Ph-prop-2-yne-1-sulfonic acid (Compound 5) is a cytotoxic pyrrolobenzodiazepine (PBD) dimer derivative. Di (MMY-SJG) -Ph-prop-2-yne-1-sulfonic acid exhibits moderate DNA alkylating activity. Di (MMY-SJG) -Ph-prop-2-yne-1-sulfonic acid can be used as the payload of ADC, thereby demonstrating strong antigen-dependent cytotoxicity[1].
Product Specifications
CAS Number
[3037777-07-1]
UNSPSC
12352005
Target
ADC Payload; DNA/RNA Synthesis
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1C2=CC(OC)=C(OCC3=CC(COC4=C(C=C5C(N=C[C@@]6([H])N(CC(C6)=C)C5=O)=C4)OC)=CC(C#CCS(=O)(O)=O)=C3)C=C2N=C[C@@]7([H])N1CC(C7)=C
Molecular Formula
C39H36N4O9S
Molecular Weight
736.79
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-176972/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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