N-Cholyl-L-threonine
N-Cholyl-L-threonine (ThrCA) is a Cholic acid conjugated with L-threonine (HY-N0658). N-Cholyl-L-threonine possesses PXR agonism activity. N-Cholyl-L-threonine can be used in the research of Crohn's disease[1].
Product Specifications
CAS Number
103444-73-1
Product Name Alternative
ThrCA
UNSPSC
12352211
Target
Drug Derivative; Pregnane X Receptor (PXR)
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(N[C@H](C(O)=O)[C@H](O)C)=O)([C@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C1)C)O)C
Molecular Formula
C28H47NO7
Molecular Weight
509.68
References & Citations
[1]Gentry EC, et al. Reverse metabolomics for the discovery of chemical structures from humans. Nature. 2024 Feb;626 (7998) :419-426.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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