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ER degrader 13

ER degrader 13 (Compound 37) is an estrogen receptor (ER) degrader. ER degrader 13 has a significant inhibitory effect on the proliferation of ER-positive breast cancer MCF-7 cells[1].

Product Specifications

CAS Number

[2839847-93-5]

UNSPSC

12352005

Target

Estrogen Receptor/ERR

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

C[C@@H]1CC2=C(C=CC3=C2OC(N3)=O)[C@@H](C4=C(F)C=C(NC5CN(CCCF)C5)C=C4F)N1CC(F)(F)F

Molecular Formula

C25H26F6N4O2

Molecular Weight

528.49

References & Citations

[1]Chenggang Zhu, et al. Estrogen receptor modulators. CN115073493A. 2024-12-10

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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