Crizotinib-amide-PEG2-NH2
Crizotinib-amide-PEG2-NH2 is a MET ligand (HY-50878) linker conjugate. Crizotinib-amide-PEG2-NH2 can be used for synthesis of MET degrader OZD-MET 01 (HY-177893) [1].
Product Specifications
CAS Number
[3048497-52-2]
UNSPSC
12352005
Target
Anaplastic lymphoma kinase (ALK) ; c-Met/HGFR; ROS Kinase; Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
C[C@@H](OC1=CC(C2=CN(N=C2)C3CCN(C(OCCOCCN)=O)CC3)=CN=C1N)C4=C(Cl)C(F)=CC=C4Cl
Molecular Formula
C26H31Cl2FN6O4
Molecular Weight
581.47
References & Citations
[1]Joo-hoon AHN, et al. Met protein degradation inducing compound. WO2024144088A1. 2025-06-27
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-176950/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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