STAT6-IN-10
STAT6-IN-10 (example 10) is a signal transducer and activator of transcription 6 (STAT6) inhibitor with an EC50 of 0.002 μM. STAT6-IN-10 inhibits CCL17 secretion in peripheral human whole blood with an IC50 of 0.095 μM. STAT6-IN-10 can be used for dermatological condition and respiratory condition research[1].
Product Specifications
CAS Number
[3092076-19-9]
UNSPSC
12352005
Target
STAT
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=NN(C)C2=CC=C(C3=CC=C(C4=NC=CN4C)C=C3)C=C12)NCC5=CC=C(NC(N(C)C)=O)C=C5
Molecular Formula
C29H29N7O2
Molecular Weight
507.59
References & Citations
[1]Chulho Cho, et al. Nitrogen-containing heteroaryl compounds for the treatment of chronic disease. WO2025133961. 2025-06-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT6
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