Demethyl-sapanisertib-C2-amide-PEG7-C2-N3

Demethyl-sapanisertib-C2-amide-PEG7-C2-N3 (Compound 10c) is an azide group linker used for coupling, which can be employed in the synthesis of "Rapa-Link" compounds, such as M-1111 (HY-176948), an mTOR inhibitor[1].

Product Specifications

CAS Number

[1887095-85-3]

UNSPSC

12352005

Target

Drug Intermediate

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCN1N=C(C2=C1N=CN=C2N)C3=CC4=C(OC(N)=N4)C=C3)=O

Molecular Formula

C33H49N11O9

Molecular Weight

743.81

References & Citations

[1]Kevan Shokat, et al. Disclosed herein, inter alia, are compounds and methods of using the same for modulating the activity of mTORCl. WO2016040806.