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PTH1R agonist 3

PTH1R agonist 3 (Example 47) is a parathyroid hormone 1 receptor (PTH1R) agonist with a pEC50 value of less than 6. PTH1R agonist 3 can be used for the study of bone diseases, such as osteoporosis[1].

Product Specifications

UNSPSC

12352005

Target

PTHR

Related Pathways

GPCR/G Protein

Field of Research

Metabolic Disease

Smiles

N/C(N)=C(C1=O)\C(N(C(N1[C@@H]2CC[C@](C)(CC2)CN3C4(C(NC3=O)=O)CCOCC4)=O)CCCC)=O

Molecular Formula

C24H36N6O6

Molecular Weight

504.58

References & Citations

[1]Du, Xiaohui, et al. Preparation of cycloalkyl- and piperidinyl-containing diaminomethylene pyrimidine-2,4,6-trione as parathyroid hormone 1 agonist. WO2025230799.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PTH1R

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