ADC-VI
ADC-VI (Compound 6) is a conjugate of a toxic molecule and a linker, in which the cytotoxin carried by CPD6 is Deruxtecan (HY-13631E) . Tricyclene is used to form an antibody-drug conjugate (ADC) by a chemical conjugation reaction through linking with an anti-FGFR2b antibody[1].
Product Specifications
CAS Number
[3031725-06-8]
UNSPSC
12352211
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
COCCOCCOCCOCCOC(C=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=C(C=C1)NC([C@H](C)NC([C@H](C(C)C)NC(CO[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)C(NCCN9C(C=CC9=O)=O)=O)=O)=O)=O
Molecular Formula
C63H77FN8O22
Molecular Weight
1317.32
References & Citations
[1]Panjiajia, et al. Resistance FGFR2b antibodies and antibody-drug conjugates. CN120424212 A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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