α-Synuclein aggregate binder 2
α-Synuclein aggregate binder 2 (Compound 1) is a specific alpha-synuclein binder with a Ki of 1.6 nM. α-Synuclein aggregate binder 2 has a weak binding affinity for β-amyloid aggregates with a Ki of 295 nM. α-Synuclein aggregate binder 2 can be used as a tracer in Parkinson's disease[1].
Product Specifications
CAS Number
3056154-68-5
UNSPSC
12352005
Target
Amyloid-β; α-synuclein
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
OC[C@@H]1N(C2=NC=CC=N2)CCN(C3=NC=C(/C=C/C4=CN=C(N5C=CN=C5)C=C4)C=N3)C1
Molecular Formula
C23H23N9O
Molecular Weight
441.49
References & Citations
[1]Idriss BENNACEF, et al. Alpha-synuclein binders and methods of use. 2025-09-06
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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