PROTAC STAT6 degrader-3
PROTAC STAT6 degrader-3 (Compound I-677) is a potent STAT6 PROTAC degrader with a DC50 of less than 1 nM. PROTAC STAT6 degrader-3 can be used for research on allergic/inflammatory diseases and cancer.
Product Specifications
CAS Number
3077385-98-6
UNSPSC
12352005
Target
PROTACs; STAT
Related Pathways
JAK/STAT Signaling; PROTAC; Stem Cell/Wnt
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(N(C)C)C(N1)=CC2=C1C(F)=C(C3=CCCN(C(CCN4N=CC=C4)=O)C3)C=C2C5=C(F)C(F)=C(N6CCN(C7=C(F)C=C(NC8CCC(NC8=O)=O)C(OC)=C7)CC6)C=C5
Molecular Formula
C44H45F4N9O5
Molecular Weight
855.88
References & Citations
[1]Bin Yang, et al. STAT6 DEGRADERS AND USES THEREOF CROSS REFERENCE TO RELATED APPLICATIONS. WO2025049820A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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