PROTAC STAT6 degrader-3
PROTAC STAT6 degrader-3 (Compound I-677) is a potent STAT6 PROTAC degrader with a DC50 of less than 1 nM. PROTAC STAT6 degrader-3 can be used for research on allergic/inflammatory diseases and cancer.
Product Specifications
CAS Number
3077385-98-6
UNSPSC
12352005
Target
PROTACs; STAT
Related Pathways
JAK/STAT Signaling; PROTAC; Stem Cell/Wnt
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(N(C)C)C(N1)=CC2=C1C(F)=C(C3=CCCN(C(CCN4N=CC=C4)=O)C3)C=C2C5=C(F)C(F)=C(N6CCN(C7=C(F)C=C(NC8CCC(NC8=O)=O)C(OC)=C7)CC6)C=C5
Molecular Formula
C44H45F4N9O5
Molecular Weight
855.88
References & Citations
[1]Bin Yang, et al. STAT6 DEGRADERS AND USES THEREOF CROSS REFERENCE TO RELATED APPLICATIONS. WO2025049820A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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