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WRN-IN-22

WRN-IN-22 (compound A01) is a potent Werner syndrome RecQ helicase (WRN) inhibitor (IC50 [1].

Product Specifications

UNSPSC

12352005

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C1C2=C(C3OC24CCN(C(C5=C(O)C=CC=N5)=O)CC4)N(C(C(NC6=CC=C(C(F)(F)F)C=C6Cl)=O)C3)C7=NC(C8=CCOCC8)=NN71

Molecular Formula

C32H27ClF3N7O6

Molecular Weight

698.05

References & Citations

[1]Ding Xiao, et al. Werner Syndrome RecQ Helicase (WRN) Inhibitors and Methods of Uses Thereof. WO2025218781A1. WIPO. 2025-10-23.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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