NSC126188
NSC126188 is a RhoB inducer. NSC126188 can induce apoptosis by inhibiting Akt/FoxO3 signaling. NSC126188 can be used for the research of cancer, such as prostate cancer[1].
Product Specifications
CAS Number
31863-82-8
UNSPSC
12352005
Target
Akt; Apoptosis; FOXO; ROCK
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton; Metabolic Enzyme/Protease; PI3K/Akt/mTOR; Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Cancer
Smiles
O=C(CCCCCCCCCCCCCCC)N1CC[N+](C)(CC1)C.[I-]
Molecular Formula
C22H45IN2O
Molecular Weight
480.51
References & Citations
[1]Won KJ, et al. NSC126188 induces apoptosis of prostate cancer PC-3 cells through inhibition of Akt membrane translocation, FoxO3a activation, and RhoB transcription. Apoptosis. 2014 Jan;19 (1) :179-90.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
FOXO3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
E-BC-K162-S-01 50 Assays (48 samples)
Magnesium (Mg) Colorimetric Assay Kit
Sign In for Pricing
View Details E-BC-K162-S-02 100 Assays (96 samples)
Magnesium (Mg) Colorimetric Assay Kit
Sign In for Pricing
View Details 
LY420167 100 µg
CEACAM20 (NM_001102598) Human Over-expression Lysate
Sign In for Pricing
View Details 
BNC040897-500 1x 500 µL
Mucin 5AC (MUC5AC) (CLH2), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details