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Mm-C3-OSu

Mm-C3-OSu (Methyl Maleate-C3-N-Hydroxysuccinimide Ester) is a structurally defined linker intermediate with a cis-configured methyl maleate (Mm) core and a C3 alkyl chain terminated by an N-hydroxysuccinimide (OSu) reactive group, designed for constructing stable antibody-drug conjugates (ADCs) .

Product Specifications

CAS Number

[2410723-30-5]

UNSPSC

12352005

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Smiles

O=C(OC)/C=C/C(NCCC(ON1C(CCC1=O)=O)=O)=O

Molecular Formula

C12H14N2O7

Molecular Weight

298.25

References & Citations

[1]Zhou, X.B., et al. Linker, Antibody-Drug Conjugate Including Same, and Use Thereof. WO 2020/035027 A1. World Intellectual Property Organization (WIPO) . 2020-02-20

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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