Cyslopentenyl cytosine triphosphoric
Cyslopentenyl cytosine triphosphoric is an active metabolite of the antitumor nucleoside analogue cyclopentenyl cytosine (CPEC) within cells. Cyslopentenyl cytosine triphosphoric can inhibit CTP synthetase and deplete the pools of cytidine nucleotides. Cyslopentenyl cytosine triphosphoric can be used for the research of cancer, such as leukemia[1].
Product Specifications
CAS Number
[135727-54-7]
Target
DNA/RNA Synthesis; Drug Metabolite
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O[C@H]1[C@H](N2C(NC(C=C2)=O)=O)C=C([C@H]1O)COP(OP(OP(O)(O)=O)(O)=O)(O)=O
Molecular Formula
C10H15N2O14P3
Molecular Weight
480.15
References & Citations
[1]Ford H Jr, et al. Cellular pharmacology of cyclopentenyl cytosine in Molt-4 lymphoblasts. Cancer Res. 1991 Jul 15;51 (14) :3733-40.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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