SMARCA2 Ligand-Linker Conjugate-4
SMARCA2 Ligand-Linker Conjugate-4 is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for SMARCA2 (HY-178414) and a PROTAC linker, which recruits E3 ligases. SMARCA2 Ligand-Linker Conjugate-4 can be used for synthesis of PROTAC SMARCA2 degrader-35 (HY-176871) [1].
Product Specifications
CAS Number
[3033001-29-2]
UNSPSC
12352005
Target
SWI/SNF Complex; Target Protein Ligand-Linker Conjugates
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Field of Research
Cancer
Smiles
OC1=C(F)C=CC=C1C2=NN=C3C(N(C[C@H](OC4=NC=C(C=O)C=C4)C5)[C@@]5(C(F)F)CN3)=C2
Molecular Formula
C22H18F3N5O3
Molecular Weight
457.41
References & Citations
[1]Corey H B, et al. BRM Targeting Compounds And Associated Methods Of Use. US20240165244A1. 2024-05-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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